Found 19 matching trials
Open Label Study With Imetelstat to Determine Effect of Imetelstat in Patients w/ Previously Treated Multiple Myeloma PHASE2 This is an open label Phase II study to determine the rate of improvement i...
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University of Maryland Medical Center - M & S Greenebaum Cancer Center
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Imetelstat as Maintenance Therapy After Initial Induction Chemotherapy in Non-small Cell Lung Cancer (NSCLC) PHASE2 The purpose of this is to evaluate the efficacy and safety of imetelstat (G...
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Achieve Clinical Research, Llc
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Safety and Dose Study of GRN163L Administered to Treat Patients With Refractory or Relapsed Multiple Myeloma PHASE1 The purpose of this study is to determine the safety and the maximum tolera...
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Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University
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Study of GRN163L With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Non Small Cell Lung Cancer PHASE1 The purpose of this study is to determine the safety and the maximum tolera...
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University of Maryland Greenebaum Cancer Center
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Open Label Study to Evaluate the Activity of Imetelstat in Patients With Essential Thrombocythemia or Polycythemia Vera PHASE2 This is a phase II open-label study of single agent imetelstat in patients ...
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Safety and Dose Study of GRN163L and Velcade to Treat Patients With Refractory or Relapsed Myeloma PHASE1 The purpose of this study is to determine safety and the maximum tolerated ...
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Karmanos Cancer Center
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Study to Evaluate Imetelstat in Patients With High-Risk MDS or AML Failing HMA-based Therapy PHASE2 The purpose of this study is to evaluate the efficacy, in terms of hematolo...
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Active Not Recruiting
Location
Royal Adelaide Hospital
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A Study Inhibiting Telomerase to Reverse Trastuzumab Resistance in HER2+ Breast Cancer PHASE1 A study to evaluate safety and biologic effects of giving GRN163L in combin...
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Indiana University Simon Cancer Center
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Study to Evaluate Activity of 2 Dose Levels of Imetelstat in Participants With Intermediate-2 or High-Risk Myelofibrosis (MF) Previously Treated With Janus Kinase (JAK) Inhibitor PHASE2 The purpose of this study is to evaluate the efficacy and safety of 2 dose ...
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Multiple Locations
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Study to Evaluate Imetelstat (GRN163L) in Participants With International Prognostic Scoring System (IPSS) Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) PHASE2 The purpose of this study is to evaluate the efficacy and safety of imetels...
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Active Not Recruiting
Location
UAB Comprehensive Cancer Center
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